Compound Overview and Structure
IGF-1 LR3 is a synthetic analogue of insulin-like growth factor-1 (IGF-1) engineered with amino acid substitutions that extend its biological half-life compared to native IGF-1. This modified peptide maintains the growth-promoting activity of endogenous IGF-1 while exhibiting reduced binding affinity to IGF binding proteins, allowing for prolonged activity in research models. The compound features an extended 83 amino acid sequence compared to the 70 amino acids found in human IGF-1, with specific modifications at the N-terminus that confer its unique pharmacokinetic profile. Researchers investigating growth factor biology can explore IGF-1 LR3’s mechanisms through Stroid UK Shop.
Research Applications in Growth Factor Biology
Scientists examine IGF-1 LR3 in various cellular and molecular biology studies focused on growth factor signalling pathways. The compound’s ability to activate IGF-1 receptors while avoiding rapid clearance makes it valuable for investigating sustained growth factor signalling in cell culture systems. Research applications include studies of myocyte proliferation, neuronal development, and cellular differentiation processes. The extended half-life allows researchers to study longer-term effects of IGF-1 receptor activation without frequent dosing schedules typical of native IGF-1. Laboratories studying IGF-1 peptide research compounds frequently utilise this analogue for mechanistic studies. Additionally, researchers investigating growth factor interactions often compare IGF-1 LR3 with other research peptides to understand differential receptor activation patterns.
Technical Specifications
| Molecular Weight | Verify with supplier |
|---|---|
| Sequence Length | 83 amino acids |
| Purity | Research grade |
| Form | Lyophilised powder |
| Quantity | 1mg per vial |
| Storage | -20°C (powder), 2-8°C (reconstituted) |
| Manufacturer | Ultima Peptides |
| CAS Number | Verify with supplier |
The compound requires proper reconstitution with bacteriostatic water or appropriate research solvents before use in experimental protocols. Researchers should note that reconstituted solutions maintain stability for limited periods and require refrigerated storage. Studies involving selective androgen receptor modulators may benefit from understanding IGF-1 LR3’s growth factor mechanisms for comparative analysis.
Research Compliance Statement
IGF-1 LR3 is intended exclusively for in-vitro laboratory research and scientific investigation purposes. This compound is not approved for human consumption, therapeutic use, or any clinical applications. Researchers must ensure compliance with institutional review boards and applicable regulations when conducting studies with this material. Laboratory personnel should follow proper safety protocols when handling research peptides and maintain appropriate documentation of experimental procedures. The compound should only be used by qualified researchers in controlled laboratory environments equipped for peptide research.
