Melanotan II Research Overview
Melanotan II is a synthetic heptapeptide analogue of alpha-melanocyte stimulating hormone (α-MSH) that has been extensively studied in melanogenesis research protocols. This cyclic peptide compound features modifications to the natural α-MSH sequence that enhance its stability and receptor binding characteristics in laboratory investigations. Research teams at Stroid UK Shop have examined its effects on melanocortin receptor pathways, particularly the MC1R and MC4R systems involved in pigmentation biology. The peptide demonstrates enhanced bioavailability compared to natural α-MSH, making it valuable for controlled laboratory studies examining melanogenesis mechanisms and photoprotective responses in cellular and animal models.
Laboratory Research Applications
Scientific investigations have focused on Melanotan II’s ability to stimulate melanogenesis through melanocortin receptor activation in experimental settings. Researchers studying peptide compounds have documented its effects on tyrosinase activity, melanin synthesis pathways, and UV response mechanisms in various model systems. The compound has been evaluated for its potential in photodermatology research, examining how synthetic melanocortin analogues influence skin pigmentation processes and cellular protection mechanisms. Additionally, studies have investigated its appetite-suppressing properties through MC4R pathway modulation, contributing to metabolic research applications. Laboratory protocols examining this peptide often involve controlled dosing regimens in animal models to assess melanogenic responses and evaluate safety profiles for future research directions.
Technical Specifications
| Parameter | Value |
|---|---|
| Peptide Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ |
| Molecular Formula | C₅₀H₆₉N₁₅O₉ |
| Molecular Weight | 1024.18 g/mol |
| Purity | ≥98% (HPLC) |
| Form | Lyophilised powder |
| Storage | -20°C (dry), 2-8°C (reconstituted) |
| Solubility | Water, saline |
| CAS Number | 121062-08-6 |
This Melanotan II peptide formulation from Axiom Peptides provides researchers with high-purity material suitable for advanced melanogenesis studies. Quality control testing ensures batch consistency and validates peptide identity through mass spectrometry and amino acid analysis. Each vial contains 10mg of lyophilised peptide, requiring reconstitution with appropriate solvents for experimental use. Storage requirements must be strictly maintained to preserve peptide integrity throughout the research period.
Research Compliance Statement
This Melanotan II peptide is supplied exclusively for in-vitro laboratory research and educational purposes. It is not intended for human consumption, therapeutic use, or any clinical applications. Researchers must comply with institutional guidelines and local regulations when handling this research chemical. All studies involving this compound should be conducted under appropriate laboratory conditions with proper safety protocols. For comprehensive research applications, scientists may consider examining this peptide alongside other selective modulators to understand broader mechanisms of cellular signalling and receptor pharmacology. This product is restricted to qualified research institutions and licensed investigators studying peptide biology and melanocortin receptor systems.

