Melanotan 2 Research Overview
Melanotan 2 is a synthetic peptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) investigated extensively in dermatological and endocrinological research applications. This cyclic heptapeptide demonstrates high binding affinity for melanocortin receptors, particularly MC1R and MC4R subtypes, making it a valuable research tool for studying melanogenesis pathways and receptor pharmacology. Researchers examining Stroid UK Shop frequently investigate Melanotan 2’s molecular mechanisms in cellular models and tissue preparations.
Laboratory Research Applications
Scientific studies examine Melanotan 2’s interactions with melanocortin receptor systems across multiple tissue types. Research protocols investigate its effects on melanogenesis in melanocyte cell cultures, examining cAMP pathway activation and tyrosinase enzyme induction. Comparative studies analyse binding kinetics against native α-MSH to evaluate receptor selectivity profiles. Researchers studying melanotropic peptides utilise this compound to investigate melanocortin signalling cascades in various experimental models. Additional research applications include examining its stability in different buffer systems and evaluating structural modifications for enhanced receptor specificity.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ |
| CAS Number | 121062-08-6 |
| Molecular Formula | C₅₀H₆₉N₁₅O₉ |
| Molecular Weight | 1024.18 g/mol |
| Purity | ≥98% (HPLC verified) |
| Form | Lyophilised powder |
| Storage | -20°C, desiccated |
This compound exhibits stability in aqueous solutions when stored at appropriate temperatures and pH conditions. Researchers investigating selective modulators often compare peptide stability profiles with other research compounds. Studies examining reconstitution protocols recommend sterile water or appropriate buffer systems for optimal solubility. Quality control testing confirms consistent molecular weight and purity specifications across research batches.
Research Compliance Information
Laboratory personnel studying research peptides must follow established institutional protocols for handling synthetic compounds. Research applications require appropriate containment measures and documentation procedures according to laboratory safety guidelines. Investigators should verify compound specifications against experimental requirements before initiating studies. This product is manufactured by Peptide Sciences under controlled laboratory conditions exclusively for in-vitro research purposes only and is not approved for human consumption, therapeutic use, or any clinical applications.
