Understanding HGH fragment
HGH Fragment 176-191 is a synthetic peptide comprising amino acids 176-191 of human growth hormone, specifically engineered to isolate the lipolytic properties of GH without its growth-promoting effects. This 16-amino acid sequence represents the C-terminal region responsible for fat metabolism regulation in preclinical models. Research teams at Stroid UK Shop investigate this fragment’s selective metabolic activity, as it retains the ability to stimulate lipolysis while eliminating the anabolic and hyperglycemic effects associated with full-length growth hormone. The peptide demonstrates stability in solution and maintains its biological activity when properly reconstituted for laboratory applications.
Research Applications
Laboratory studies examine HGH Fragment 176-191’s mechanism of action through its binding to growth hormone receptors specifically involved in lipid metabolism pathways. Researchers analyse its effects on adipocyte function, investigating how this peptide modulates cyclic adenosine monophosphate (cAMP) levels and subsequent activation of hormone-sensitive lipase. The fragment’s selectivity makes it valuable for studying metabolic processes without the confounding variables introduced by growth hormone’s broader physiological effects. Scientists working with fragment peptides often compare its activity profile against other selective androgen receptor modulators and bioactive peptides in metabolic research protocols. Cell culture studies examine dose-response relationships and temporal effects on lipolytic enzyme activity.
Product Specifications
| Parameter | Specification |
|---|---|
| Sequence | Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe |
| Molecular Weight | 1815.08 g/mol |
| CAS Number | Verify with supplier |
| Purity | ≥98% by HPLC |
| Form | Lyophilised white powder |
| Storage | -20°C, protect from light and moisture |
| Solubility | Water, bacteriostatic water, saline |
| Stability | 2-3 years lyophilised, 30 days reconstituted (2-8°C) |
Research Compliance
This HGH Fragment 176-191 10mg preparation is manufactured exclusively for in-vitro research applications and is not intended for human consumption, clinical use, or therapeutic applications. Research institutions must ensure proper handling protocols and maintain appropriate documentation for all experimental procedures involving this peptide. The product is supplied for legitimate scientific investigation only, and researchers are responsible for compliance with all applicable regulations governing peptide research in their jurisdiction.

