Research Overview of Atorvastatin Compound
Atorvastatin is a synthetic HMG-CoA reductase inhibitor extensively studied in cardiovascular and metabolic research. This statin-class compound operates through competitive inhibition of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, the rate-limiting enzyme in cholesterol biosynthesis. Laboratory researchers examining lipid metabolism pathways can investigate atorvastatin’s molecular mechanisms in cellular models. The compound demonstrates high selectivity for hepatic tissue in preclinical studies, making it valuable for examining tissue-specific metabolic responses. Research applications include investigating pleiotropic effects beyond cholesterol reduction, including anti-inflammatory properties and endothelial function modulation in vitro.
Laboratory Applications
Researchers at Stroid UK Shop utilise atorvastatin to examine multiple biochemical pathways. Cell culture studies investigate the compound’s effects on sterol regulatory element-binding protein (SREBP) activation and downstream gene expression. Comparative analyses with other hypolipidemic compounds enable researchers to evaluate mechanism-specific responses. The compound’s water solubility characteristics facilitate preparation of precise research solutions. Advanced research protocols examine atorvastatin’s interaction with cytochrome P450 enzymes, particularly CYP3A4 metabolism pathways. Studies investigating combination effects with selective androgen receptor modulators or research peptides provide insights into multi-pathway metabolic regulation.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 134523-00-5 |
| Molecular Formula | C₃₃H₃₅FN₂O₅ |
| Molecular Weight | 558.64 g/mol |
| Chemical Name | [R-(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid |
| Storage | Room temperature, dry conditions |
| Solubility | Water, methanol, DMSO |
Research Compliance Information
This atorvastatin research material is supplied exclusively for in-vitro laboratory research purposes. The compound is not intended for human consumption, therapeutic use, or any application outside controlled laboratory environments. Researchers must ensure proper handling protocols and waste disposal procedures according to institutional guidelines. All studies should be conducted by qualified personnel with appropriate safety measures. This product is not approved for human clinical trials or medical applications.
