Research Overview of Andarine (S-4)
Andarine (S-4) is a non-steroidal selective androgen receptor modulator (SARM) belonging to the aryl-propionamide class of research compounds. Originally developed for investigating muscle-wasting conditions and osteoporosis models, this compound demonstrates partial agonist activity at androgen receptors with notable tissue selectivity. Researchers at Stroid UK Shop can examine S-4’s unique receptor binding profile, which shows preferential affinity for bone and muscle tissue over prostate tissue in animal studies. The compound’s development history includes progression through Phase I clinical trials before discontinuation, providing valuable reference data for contemporary research applications. Magnus Pharmaceuticals has formulated this research-grade material to exacting specifications for laboratory investigations examining selective androgen receptor modulation mechanisms.
Laboratory Applications
Research scientists utilise Andarine to investigate selective tissue targeting in androgen receptor biology. Studies have examined its partial agonist properties, which produce distinct activation patterns compared to full agonists like testosterone. The compound serves as a valuable tool for examining dose-dependent receptor modulation in muscle and bone tissue models. Investigators studying osteoporosis mechanisms often evaluate S-4’s effects on bone mineral density markers in preclinical systems. Andarine research compounds enable comparative studies alongside other selective modulators. Research applications extend to examining myofibrillar protein synthesis pathways and examining potential protective effects against muscle atrophy in disease models. Scientists investigating hormonal signalling cascades utilise this compound to study tissue-specific androgen receptor activation patterns. The research community has documented extensive data on S-4’s bioavailability and metabolic pathways, making it valuable for pharmacokinetic studies. Comparative analyses with other SARM compounds and peptide modulators provide insights into receptor selectivity mechanisms.
Specification Data
| Parameter | Value |
|---|---|
| Chemical Name | Andarine (S-4) |
| CAS Registry | 401900-40-1 |
| Molecular Formula | C₁₉H₁₈F₃N₃O₆ |
| Molecular Weight | 441.36 g/mol |
| Classification | Non-steroidal SARM |
| Mechanism | Partial AR agonist |
| Manufacturer | Magnus Pharmaceuticals |
| Storage Conditions | Room temperature, protect from light |
Research Compliance Statement
This Andarine (S-4) product from Magnus Pharmaceuticals is manufactured exclusively for in-vitro research and laboratory applications. The compound is not intended for human consumption, therapeutic use, or any application outside controlled research environments. Researchers must maintain appropriate safety protocols and regulatory compliance when handling this material. All investigations should follow institutional guidelines for research chemical usage and disposal procedures.
