Telmisartan Research Overview
Telma 80 mg is a pharmaceutical-grade formulation containing telmisartan, an angiotensin II receptor antagonist manufactured by Glenmark Pharmaceuticals Ltd. This selective AT1 receptor blocker represents a key research tool for investigating renin-angiotensin system modulation in laboratory studies. Research scientists at Stroid UK Shop examine telmisartan’s mechanism of action through its selective binding to angiotensin II type 1 receptors, demonstrating high affinity and insurmountable antagonism in cellular assays. The compound exhibits unique pharmacokinetic properties with extended tissue residence time, making it valuable for sustained receptor occupancy studies in experimental models.
Laboratory Research Applications
Investigators study telmisartan’s cardiovascular protective mechanisms beyond blood pressure modulation, including its partial agonist activity at peroxisome proliferator-activated receptor gamma (PPARγ). Research applications encompass endothelial function studies, oxidative stress investigations, and metabolic pathway analysis in cell culture systems. Scientists explore its anti-inflammatory properties through nuclear factor-kappa B pathway inhibition and examine its effects on glucose metabolism in hepatocyte cultures. The compound serves as a reference standard in telmisartan research protocols, enabling comparison with other ARB compounds in receptor binding assays. Researchers investigating cardiovascular disease models utilise telmisartan to examine angiotensin II-mediated cellular responses and downstream signaling cascades.
Technical Specifications
| Parameter | Value |
|---|---|
| Active Ingredient | Telmisartan 80mg |
| Manufacturer | Glenmark Pharmaceuticals Ltd. |
| Molecular Formula | C₃₃H₃₀N₄O₂ |
| Molecular Weight | 514.62 g/mol |
| CAS Number | 144701-48-4 |
| Storage | Room temperature, dry conditions |
| Solubility | Practically insoluble in water |
Research laboratories studying selective receptor modulators often compare telmisartan’s selectivity profile with other pharmaceutical compounds. Advanced researchers examining peptide-based therapeutics utilise telmisartan as a small-molecule control in receptor specificity studies.
Research Compliance Statement
Telma 80mg is supplied exclusively for in-vitro research applications and laboratory studies. This pharmaceutical compound is not intended for human consumption, clinical use, or therapeutic applications. Researchers must maintain appropriate laboratory safety protocols and comply with institutional guidelines for pharmaceutical research materials. All studies should be conducted within controlled laboratory environments by qualified research personnel.
