Research Overview of Tadalafil Citrate
Tadalafil citrate is a selective phosphodiesterase type 5 (PDE5) enzyme inhibitor extensively utilised in cardiovascular and smooth muscle research applications. This laboratory compound demonstrates potent inhibitory activity against PDE5 enzymes, making it a valuable tool for investigating nitric oxide signalling pathways and cyclic guanosine monophosphate (cGMP) mediation in research models. Manufactured by Odin Pharmaceuticals to pharmaceutical standards, these tablets provide researchers with consistent material for examining vascular smooth muscle relaxation mechanisms and endothelial function studies.
Research scientists studying cardiovascular physiology frequently investigate tadalafil’s extended half-life properties compared to other PDE5 inhibitors. The compound’s unique pharmacokinetic profile enables prolonged experimental observation periods, making it particularly suitable for time-course studies examining vascular reactivity and smooth muscle function. Laboratory investigations have examined its selectivity profile against other phosphodiesterase enzymes, contributing to understanding of tissue-specific PDE5 inhibition mechanisms.
Laboratory Applications
Primary research applications include vascular biology studies examining smooth muscle contractility, endothelial nitric oxide synthase pathway investigations, and pulmonary vascular resistance research. Scientists at Stroid UK Shop examine tadalafil’s effects on cyclic nucleotide signalling in isolated tissue preparations and cellular models. The compound serves as a valuable reference standard in comparative PDE5 inhibitor studies and mechanism-of-action research.
Advanced research protocols investigate tadalafil’s potential cardioprotective properties in ischaemia-reperfusion models and its effects on pulmonary arterial smooth muscle in hypoxic conditions. Research teams studying erectile dysfunction therapeutics examine corpus cavernosum tissue responses and penile blood flow mechanisms. Additional investigations explore its utility in studying platelet aggregation inhibition and potential neuroprotective pathways through enhanced cerebral blood flow.
Product Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Tadalafil Citrate |
| CAS Number | 171596-29-5 |
| Molecular Formula | C₂₂H₁₉N₃O₄ |
| Molecular Weight | 389.4 g/mol |
| Form | Oral Tablets |
| Manufacturer | Odin Pharmaceuticals |
| Package | 20 Tablets |
| Storage | Room temperature, dry |
This research material complements other laboratory compounds available including selective androgen receptor modulators and research peptides for comprehensive molecular biology studies.
Research Compliance
This tadalafil citrate material is supplied strictly for in-vitro laboratory research purposes only. This compound is not intended for human consumption, therapeutic use, or any application outside controlled laboratory environments. Researchers must ensure appropriate institutional oversight and safety protocols when handling this material. All studies should be conducted within approved research facilities with proper waste disposal procedures.

