Compound Profile: Tadalafil C20 Pharmaceutical
Tadalafil C20 Pharmaceutical is a phosphodiesterase type 5 (PDE-5) inhibitor extensively studied in cardiovascular and vascular research applications. This pharmaceutical-grade compound represents a selective inhibitor of the PDE-5 enzyme, which plays a crucial role in cyclic guanosine monophosphate (cGMP) metabolism within vascular smooth muscle tissue. Originally developed as a clinical therapeutic, tadalafil has become an important research tool for investigating nitric oxide-dependent signalling pathways and vascular function in laboratory settings. The compound’s mechanism involves selective inhibition of PDE-5, preventing the breakdown of cGMP and thereby maintaining vasodilatory responses in experimental models. Researchers at Stroid UK Shop utilise tadalafil in various cardiovascular studies examining endothelial function and smooth muscle physiology.
Research Applications
In laboratory investigations, tadalafil serves as a valuable tool for examining vascular biology and cardiovascular physiology. Research applications include studying nitric oxide-cGMP signalling cascades, investigating endothelial dysfunction models, and evaluating vascular smooth muscle contractility responses. The compound’s long half-life characteristics make it particularly suitable for extended experimental protocols examining sustained vascular effects. Scientists frequently employ tadalafil in comparative studies alongside other PDE-5 inhibitors to evaluate selectivity profiles and dose-response relationships. Additional research contexts include pulmonary vascular studies, where tadalafil’s effects on pulmonary artery pressure and resistance are investigated. The compound’s well-characterised pharmacological profile makes it an excellent reference standard for developing novel PDE-5 modulators. Researchers also investigate tadalafil’s potential cardiovascular protective effects and its interactions with other signalling pathways beyond the classical NO-cGMP axis, expanding into studies involving selective modulators and bioactive peptides for comprehensive vascular research programmes.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | Tadalafil |
| CAS Number | 171596-29-5 |
| Molecular Formula | C₂₂H₁₉N₃O₄ |
| Molecular Weight | 389.40 g/mol |
| Purity | Pharmaceutical grade |
| Solubility | DMSO, ethanol (limited aqueous) |
| Storage | Room temperature, dry, protected from light |
| Stability | Stable under recommended storage conditions |
Research Compliance
Tadalafil C20 Pharmaceutical is supplied exclusively for in-vitro research purposes and laboratory investigations. This product is not intended for human consumption, therapeutic use, or any application outside controlled scientific research environments. Researchers must ensure appropriate institutional oversight, proper safety protocols, and compliance with local regulations when handling this compound. All studies should be conducted within approved laboratory facilities by qualified personnel familiar with pharmaceutical research compounds and safety procedures.
