Pharmaceutical Compound Overview
Losartan is an angiotensin II receptor type 1 (AT1) antagonist belonging to the class of antihypertensive agents known as angiotensin receptor blockers (ARBs). This pharmaceutical compound from Intas Pharmaceuticals represents a well-characterised research tool for investigating renin-angiotensin-aldosterone system (RAAS) modulation in cardiovascular research models. Losartan demonstrates selective antagonism at AT1 receptors while leaving AT2 receptors unaffected, providing researchers at Stroid UK Shop with a precise mechanism for studying angiotensin II pathway interventions.
The compound’s molecular structure enables competitive inhibition of angiotensin II binding, effectively blocking vasoconstriction and aldosterone secretion pathways that are central to blood pressure regulation research. Each 25mg tablet provides standardised dosing for experimental protocols examining cardiovascular physiology, renal function, and hypertensive disease models. Researchers investigating metabolic pathways may also find value in our comprehensive SARMs collection for comparative studies on tissue-selective receptor modulation.
Research Applications in Laboratory Models
Academic institutions and research laboratories utilise losartan extensively in preclinical studies investigating cardiovascular pathophysiology and therapeutic interventions. The compound’s well-documented pharmacokinetic profile includes rapid oral absorption, hepatic metabolism via cytochrome P450 enzymes, and conversion to the active metabolite EXP3174, which exhibits greater AT1 receptor affinity than the parent compound. Research teams studying hypertension models, cardiac remodelling, and nephroprotective mechanisms find losartan invaluable for examining RAAS-mediated pathways.
Contemporary research applications extend to diabetic nephropathy studies, where losartan’s renoprotective properties are investigated independently of blood pressure effects. Cardiovascular researchers exploring our peptides range often incorporate losartan as a positive control in studies examining angiotensin-related peptide signalling. The compound’s established safety profile and extensive literature database make it an essential reference standard for laboratories developing novel cardiovascular therapeutics and studying receptor selectivity within the losartan and other drugs category.
Pharmaceutical Specifications
| Parameter | Specification |
|---|---|
| Active Ingredient | Losartan Potassium |
| Strength | 25mg per tablet |
| CAS Number | 114798-26-4 |
| Molecular Formula | C₂₂H₂₂ClKN₆O |
| Molecular Weight | 461.00 g/mol |
| Manufacturer | Intas Pharmaceuticals |
| Form | Oral tablet |
| Storage Conditions | Room temperature, dry place |
Research Compliance Statement
Losartas 25mg tablets are supplied by stroidukshop.co.uk strictly for in-vitro research and laboratory analytical purposes only. This pharmaceutical product is not intended for human consumption, clinical use, or therapeutic application. Researchers must ensure compliance with institutional guidelines, local regulations, and laboratory safety protocols when handling this compound. All studies should be conducted under appropriate supervision within licensed research facilities.
