Pharmaceutical-Grade Atorvastatin Research Compound
Lipitor 20 is a pharmaceutical statin compound manufactured by Pfizer, containing atorvastatin calcium as the active ingredient. This well-established HMG-CoA reductase inhibitor has been extensively studied in laboratory settings for its effects on cholesterol biosynthesis pathways and lipid metabolism regulation. Researchers at Stroid UK Shop can examine this compound’s mechanism of action in competitive inhibition studies of the rate-limiting enzyme in cholesterol synthesis.
The compound operates through selective binding to the active site of HMG-CoA reductase, effectively blocking the conversion of 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate. This mechanism makes it valuable for investigating downstream effects on cellular cholesterol homeostasis, including upregulation of LDL receptor expression and modulation of sterol regulatory element-binding proteins. Laboratory studies have demonstrated its potency compared to other statins, with IC50 values in the nanomolar range for enzyme inhibition assays.
Laboratory Research Applications
Researchers utilise Lipitor 20 in diverse experimental protocols examining cardiovascular biochemistry and lipid metabolism. Cell culture studies investigate its effects on hepatocyte cholesterol production, while enzyme kinetics research examines competitive inhibition parameters against HMG-CoA reductase. The compound serves as a reference standard in hypolipidemic drug studies, allowing comparison with experimental cholesterol-lowering agents under development.
Beyond cholesterol research, investigators examine pleiotropic effects including anti-inflammatory pathways, endothelial function modulation, and oxidative stress mechanisms. These studies complement primary lipid research by exploring broader cellular effects. Laboratories studying drug interactions often investigate this compound alongside selective androgen receptor modulators or research peptides to understand metabolic pathway crosstalk in controlled experimental conditions.
Compound Specifications
| Parameter | Specification |
|---|---|
| Active Ingredient | Atorvastatin Calcium |
| Strength | 20mg per unit |
| Manufacturer | Pfizer |
| CAS Number | 134523-00-5 |
| Molecular Formula | C₃₃H₃₄FN₂O₅·Ca |
| Storage Requirements | Room temperature, dry conditions |
Research Compliance Statement
Lipitor 20 is supplied exclusively for in-vitro research applications and laboratory analysis. This pharmaceutical compound is intended for qualified researchers investigating cholesterol biosynthesis, enzyme inhibition mechanisms, and cardiovascular biochemistry pathways. Not intended for human consumption, clinical use, or therapeutic applications. Researchers must comply with institutional guidelines and maintain appropriate laboratory safety protocols when handling this research compound.
