Product Overview: Ketotifen Sopharma
Ketotifen Sopharma is a potent second-generation H1-antihistamine compound extensively investigated for its dual mechanism of action as both an antihistamine and mast cell stabiliser. This benzocycloheptathiophene derivative demonstrates unique pharmacological properties that distinguish it from conventional antihistamines in laboratory research. Ketotifen exhibits selective antagonism at histamine H1 receptors while simultaneously inhibiting calcium influx into mast cells, preventing degranulation and subsequent mediator release. Research studies have demonstrated its ability to modulate inflammatory cascades through multiple pathways, making it a valuable tool for investigating allergic response mechanisms and inflammatory mediator interactions. The compound’s molecular structure enables researchers to examine histamine receptor binding kinetics and evaluate downstream signalling pathways in cellular models. Stroid UK Shop supports advanced biochemical investigations across multiple therapeutic areas.
Laboratory Applications
Research applications for Ketotifen encompass broad immunological and pharmacological studies examining histamine-mediated responses and inflammatory pathway modulation. Laboratory investigations utilise this compound to study mast cell biology, evaluating degranulation mechanisms and calcium-dependent cellular processes. Researchers analyse its effects on cytokine production, examining how H1-receptor antagonism influences inflammatory mediator release in various cell culture systems. The compound serves as a reference standard in specialised antihistamine research, enabling comparative studies with other H1-antagonists and mast cell stabilisers. Pharmacokinetic studies examine its absorption, distribution, and metabolic pathways, while receptor binding assays investigate its selectivity profiles. Advanced research protocols evaluate its potential interactions with other pharmaceutical compounds, particularly in studies examining polypharmacy effects. Immunological research employs Ketotifen to investigate allergic response mechanisms, studying how mast cell stabilisation affects overall inflammatory responses. The compound’s dual mechanism provides researchers with opportunities to examine both immediate hypersensitivity reactions and delayed inflammatory processes in controlled laboratory environments.
Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 34580-13-7 |
| Molecular Formula | C₁₉H₁₉NOS |
| Molecular Weight | 309.42 g/mol |
| Chemical Name | 4,9-Dihydro-4-(1-methyl-4-piperidinylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one |
| Appearance | White to off-white tablet |
| Storage | Room temperature, dry conditions, protected from light |
| Solubility | Soluble in organic solvents, limited aqueous solubility |
Research investigations benefit from studying Ketotifen alongside other compounds available in our SARM research collection and peptide research portfolio, enabling comprehensive multi-pathway studies examining various cellular and molecular mechanisms.
Research Compliance
This product is manufactured by Sopharma specifically for in-vitro research applications only. Ketotifen Sopharma is intended solely for qualified researchers conducting laboratory studies and is not approved for human consumption, clinical use, or any therapeutic applications. Researchers must maintain proper laboratory protocols, safety procedures, and regulatory compliance when handling this compound. All studies should be conducted in appropriate research facilities with adequate safety measures and documentation procedures.
