Overview of Glucophage LONG 1000
Glucophage LONG 1000 is a sustained-release metformin hydrochloride formulation developed by pharmaceutical manufacturer Merck. This extended-release preparation delivers the biguanide compound metformin in a controlled-release matrix, designed for prolonged compound exposure in laboratory research applications. The formulation represents advanced pharmaceutical technology for studying glucose metabolism pathways and cellular energy regulation mechanisms. Research laboratories investigating metabolic syndrome models and cellular glucose uptake mechanisms benefit from the extended pharmacokinetic profile this formulation provides. When researchers examine cellular responses to metformin exposure, the sustained-release characteristics allow for more physiologically relevant experimental conditions compared to immediate-release preparations.
Research Applications in Metabolic Studies
Laboratory investigations utilise Glucophage LONG 1000 to study AMPK pathway activation, glucose transporter expression, and mitochondrial respiratory complex modulation in cell culture systems. The extended-release formulation proves particularly valuable for researchers examining chronic exposure effects on hepatocyte glucose production and skeletal muscle glucose uptake mechanisms. Comparative studies between immediate and sustained-release metformin formulations provide insights into dose-response relationships and temporal kinetics of metabolic pathway modulation. Scientists investigating insulin sensitisation pathways analyse how prolonged metformin exposure affects cellular signalling cascades in primary cell cultures. Research applications extend to studying metformin’s effects on inflammatory marker expression and oxidative stress responses in various cell lines. Our Stroid UK Shop provides laboratory-grade compounds for scientific investigation. The sustained-release characteristics make this formulation ideal for studies requiring consistent compound exposure over extended timeframes. Researchers examining metabolic modulators can explore our metformin research compounds for comparative studies. Additional metabolic research compounds are available in our SARMs category and peptides section for comprehensive metabolic pathway investigations.
Technical Specifications
| Parameter | Specification |
|---|---|
| Active Compound | Metformin Hydrochloride |
| Formulation | Extended-Release Tablets |
| Strength | 1000mg per tablet |
| Manufacturer | Merck |
| CAS Number | 1115-70-4 |
| Molecular Formula | C₄H₁₁N₅·HCl |
| Molecular Weight | 165.62 g/mol |
| Storage Conditions | Room temperature, dry environment |
| Research Applications | Metabolic pathway studies, glucose regulation |
Research Compliance Statement
Glucophage LONG 1000 Merck is supplied exclusively for in-vitro laboratory research applications and scientific investigation purposes. This product is not intended for human consumption, therapeutic use, or any application outside controlled laboratory environments. Researchers must possess appropriate laboratory facilities and expertise for handling pharmaceutical-grade research compounds. All experimental protocols should follow institutional guidelines for laboratory safety and compound handling procedures. This sustained-release metformin formulation is provided for academic and commercial research institutions conducting legitimate scientific studies on metabolic pathways and cellular glucose regulation mechanisms.
