ALDACTONE 100 Pharmacia & Upjohn: Compound Profile
Aldactone 100 is a pharmaceutical preparation containing spironolactone, a potassium-sparing diuretic classified as an aldosterone receptor antagonist. Spironolactone operates through competitive inhibition of aldosterone at mineralocorticoid receptors in renal tubular cells, making it valuable for investigating renal electrolyte handling and cardiovascular physiology in controlled laboratory environments. This Pharmacia & Upjohn formulation provides researchers with a standardised reference compound for examining diuretic mechanisms and aldosterone-mediated pathways. Laboratory studies frequently investigate spironolactone’s role in potassium retention, sodium excretion, and its broader implications for fluid balance research. Scientists at Stroid UK Shop can examine this compound’s pharmacological properties alongside other research chemicals.
Laboratory Applications
Research applications for Aldactone 100 encompass cardiovascular physiology studies, particularly investigating heart failure models and hypertension research protocols. Scientists examine spironolactone’s effects on renin-angiotensin-aldosterone system modulation in cellular and tissue-based assays. The compound serves as a reference standard for studying mineralocorticoid receptor binding kinetics and downstream signalling pathways. Endocrine research protocols investigate spironolactone’s anti-androgenic properties through its binding to androgen receptors, making it relevant for hormonal pathway studies. Researchers working with diuretic compounds frequently compare spironolactone against thiazide and loop diuretics to understand differential mechanisms. Comparative studies with selective androgen receptor modulators examine tissue-specific receptor interactions. Additionally, investigations into metabolic pathways often incorporate findings from peptide research to understand comprehensive hormonal networks.
Product Specifications
| Active Ingredient | Spironolactone 100mg |
|---|---|
| Manufacturer | Pharmacia & Upjohn |
| Chemical Formula | C₂₄H₃₂O₄S |
| Molecular Weight | 416.57 g/mol |
| CAS Number | 52-01-7 |
| Storage Requirements | Room temperature, dry environment |
| Solubility | Limited water solubility, DMSO compatible |
Research Compliance
This Aldactone 100 pharmaceutical preparation is supplied exclusively for in-vitro laboratory research purposes. The product is intended for qualified researchers studying diuretic mechanisms, aldosterone receptor interactions, and related pharmacological pathways in controlled laboratory settings. This compound is not approved for human consumption, therapeutic use, or any application outside legitimate scientific research protocols. Researchers must ensure compliance with institutional guidelines and applicable regulations when conducting studies with this research material.
