Tacrolimus Research Overview
Prograf 5mg by Astellas Pharma contains tacrolimus, a macrolide lactone immunosuppressive compound originally isolated from Streptomyces tsukubaensis. This pharmaceutical-grade preparation enables researchers to investigate immune system suppression mechanisms and transplant rejection pathways in controlled laboratory environments. Studies examining tacrolimus focus on its role as a calcineurin inhibitor that blocks T-lymphocyte activation through interference with calcium-dependent signalling cascades. Research applications at Stroid UK Shop support academic institutions and laboratories studying immunosuppressive compound mechanisms.
Research Applications
Tacrolimus research encompasses multiple therapeutic areas including organ transplantation immunology, autoimmune disease mechanisms, and inflammatory pathway modulation. Laboratory studies examine how tacrolimus binds to FK506-binding protein 12 (FKBP-12) to form complexes that inhibit calcineurin phosphatase activity. Researchers investigate dose-response relationships, pharmacokinetic profiles, and tissue distribution patterns in preclinical models. Comparative studies evaluate tacrolimus alongside other immunosuppressants available in our tacrolimus research category. Advanced research protocols examine combination therapies and investigate mechanisms underlying therapeutic drug monitoring requirements in clinical immunosuppression.
Product Specifications
| Parameter | Specification |
|---|---|
| Active Ingredient | Tacrolimus |
| Strength | 5mg per capsule |
| Manufacturer | Astellas Pharma |
| CAS Number | 104987-11-3 |
| Molecular Formula | C₄₄H₆₉NO₁₂ |
| Molecular Weight | 804.02 g/mol |
| Storage Temperature | Room temperature, dry conditions |
This pharmaceutical preparation offers researchers standardised tacrolimus content for reproducible experimental protocols. Quality control specifications ensure consistent results across research batches, supporting reliable comparative studies with compounds from our selective androgen receptor modulator and peptide research collections.
Laboratory Use and Compliance
Prograf 5mg capsules are manufactured under pharmaceutical standards for research applications examining immunosuppressive mechanisms in controlled laboratory settings. Each batch undergoes rigorous testing to verify tacrolimus content and purity levels suitable for academic research protocols. Storage recommendations include maintaining capsules at room temperature in dry conditions away from direct light exposure to preserve compound stability throughout research timeframes. This product is intended exclusively for in-vitro research applications and is not approved for human consumption or therapeutic use. Researchers should follow institutional guidelines for handling immunosuppressive compounds and maintain appropriate safety protocols during experimental procedures.
