About Xtane
Exemestane is a steroidal aromatase inhibitor belonging to the androstenedione analogue class. This compound functions as an irreversible, suicide inhibitor of the aromatase enzyme (CYP19A1), making it a valuable research tool for investigating estrogen biosynthesis pathways. Unlike reversible inhibitors, exemestane forms covalent bonds with the aromatase active site, providing sustained enzyme inhibition in laboratory models. Researchers at Stroid UK Shop utilise this compound to examine hormonal feedback mechanisms and study the effects of aromatase inhibition on cellular processes.
Laboratory Applications
Scientific investigations with exemestane focus on its mechanism as a Type I aromatase inhibitor. Research models demonstrate its capacity to reduce estradiol synthesis by permanently inactivating the aromatase enzyme through mechanism-based inhibition. Studies examine its pharmacokinetic profile, including its active metabolite 17-hydroxyexemestane, which retains aromatase-inhibitory activity. Laboratory protocols investigate dose-response relationships, tissue distribution patterns, and metabolic pathways. Comparative studies with other compounds from our aromatase inhibitor collection help researchers understand differential mechanisms of enzyme inhibition and their applications in endocrine research.
Product Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 6-Methylideneandrosta-1,4-diene-3,17-dione |
| CAS Number | 107868-30-4 |
| Molecular Formula | C₂₀H₂₄O₂ |
| Molecular Weight | 296.40 g/mol |
| Dosage Strength | 25 mg per tablet |
| Manufacturer | Natco Pharmaceuticals Ltd |
| Storage Requirements | Room temperature, dry environment |
This compound complements other research categories including selective androgen receptor modulators and peptide compounds for comprehensive endocrine system studies.
Research Use Compliance
This exemestane product is supplied exclusively for in-vitro laboratory research and analytical testing purposes. The compound is not intended for human consumption, therapeutic use, or any application outside of controlled scientific environments. Researchers must ensure appropriate laboratory safety protocols and regulatory compliance when handling this material. All studies should be conducted by qualified personnel within properly equipped research facilities following institutional guidelines for chemical safety and disposal procedures.
